Alkoxylation

This dataset reports the biocatalytic oxidation of benzyl alcohol by a copper radical oxidase (AlkOx). The effects of enzyme loading, cocatalyst loading, and pH balance on both initial rate and total conversion were assayed. 1

The dataset includes 104 samples with four parameters and one objective.

Feature	Kind	Settings	Description
Catalase	continuous	[ 0.05, 1.0]	concentration [μM]
Peroxidase	continuous	[ 0.5, 10.0]	concentration [μM]
Alcohol oxidase	continuous	[ 2.0, 8.0]	concentration [nM]
pH	continuous	[ 6, 8]	-log(H+)

Objective	Kind	Goal
conversion	continuous	maximize

Reference

1

6. Häse, M. Aldeghi, R.J. Hickman, L.M. Roch, M. Christensen, E. Liles, J.E. Hein, A. Aspuru-Guzik. Olympus: a benchmarking framework for noisy optimization and experiment planning. arXiv (2020), 2010.04153.